Follow these simple steps to make your Chicken and Spinach Casserole with Cream Cheese:

1. Prep the Oven: Preheat your oven to 350°F (175°C) and lightly grease a 9×13-inch casserole dish with cooking spray or oil.
2. Cook the Chicken: If you haven’t already, cook your chicken. You can bake, boil, or sauté it until fully cooked. Then shred or chop it into bite-sized pieces.
3. Sauté the Vegetables: In a skillet, heat a small amount of oil over medium heat. Add the chopped onion and minced garlic, sautéing until the onion becomes translucent.
4. Prepare the Filling: In a large bowl, combine the softened cream cheese, sour cream, cheddar cheese, onion, garlic, shredded chicken, chopped spinach, onion powder, garlic powder, salt, and pepper. Mix well until all ingredients are thoroughly combined.
5. Spread in Dish: Transfer the mixture into the prepared casserole dish, spreading it evenly.
6. Add Toppings: If desired, sprinkle breadcrumbs evenly over the top for an additional crunch.
7. Bake: Place the casserole in the preheated oven and bake for 35-40 minutes or until the filling is hot and the top is golden brown.
8. Let It Rest: Once done, remove the casserole from the oven and allow it to sit for 5-10 minutes before serving. This resting time helps set the filling.

Voila! You have created a delightful Chicken and Spinach Casserole with Cream Cheese that will surely impress!